When you’re pregnant, even a simple headache or mild fever can raise questions about what’s safe to take. Many medications are off-limits during pregnancy — but one option that continues to be considered safe and effective is acetaminophen, also known by the brand name Tylenol. According to the American College of Obstetricians and Gynecologists (ACOG), acetaminophen remains the preferred pain reliever and fever reducer for use during pregnancy when taken as directed.
What ACOG Says
In its most recent guidance, ACOG emphasizes the following key points:
● Acetaminophen is considered safe for short-term use during pregnancy when taken at the lowest effective dose and for the shortest necessary duration.
● There is no proven evidence that occasional acetaminophen use causes neurodevelopmental conditions such as autism or ADHD.
● Untreated pain or fever during pregnancy can itself be harmful, increasing risks such as dehydration, stress, and elevated body temperature — which can affect both mother and baby.
“The available studies do not provide conclusive evidence that acetaminophen use during pregnancy causes developmental issues in children.” — American College of Obstetricians and Gynecologists (ACOG, 2025) For those interested, ACOG’s full statements on this topic can be found at acog.org.
Safe Use Guidelines
If your healthcare provider recommends acetaminophen during pregnancy, here are a few best practices:
● Always follow your provider’s instructions on dosage and frequency.
● Avoid combination cold or flu medicines that may contain acetaminophen along with other ingredients not recommended in pregnancy.
● Use only when necessary, and stop once symptoms improve.
● Keep your provider informed about any medications, supplements, or herbal products you’re using.
The Bottom Line
When used appropriately, acetaminophen (Tylenol) remains a trusted and safe option for relieving pain or fever during pregnancy. While research on medications is always evolving, current medical evidence, and ACOG’s expert review, continue to support its safety when taken responsibly.
As always, talk with your healthcare provider before taking any medication, even those available over the counter. They can help you determine what’s best for you and your baby.
This blog post is meant to be informational and is not medical advice.
